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It is an investigational triple agonist (GLP-1, GIP, and glucagon receptors) not yet approved by the MHRA for use in the UK as of mid-2025
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(2016) published in Diabetes Care evaluated the addition of a DPP-4 inhibitor to existing GLP-1 receptor agonist therapy and found no significant additional reduction in HbA1c compared to GLP-1 agonist monotherapy
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